Primarily orofacial. Use General Antiseptic program.Encyclopedia Entry for Herpes Simplex :Herpes Simplex. May cause : Alzheimer's diseaseBipolar disorderCoronary heart diseaseDementiaMetabolic syndromeInformation from Marcello Allegretti.Encyclopedia Entry for Herpes Simplex :Herpes simplex. Source of disease: Herpes simplex virus 1 and 2 (HSV-1 and HSV-2)