Excess aldosterone produced by the adrenal glands - can lead to low blood potassium levels (hypokalemia).Encyclopedia Entry for Hyperaldosteronism :Hyperaldosteronism - primary and secondary. Primary hyperaldosteronism is due to a problem of the adrenal glands themselves, which causes them to release too much aldosterone. In contrast, with secondary hyperaldosteronism, a problem elsewhere in the body causes the adrenal glands to release too much aldosterone. These problems can be with genes, diet, or a medical disorder such as with the heart, liver, kidneys, or high blood pressure. Most cases of primary hyperaldosteronism are caused by a noncancerous (benign) tumor of the adrenal gland. The condition is most common in people 30 to 50 years old.Primary and secondary hyperaldosteronism have common symptoms, including: High blood pressure Low level of potassium in the blood Feeling tired all the time Headache Muscle weakness Numbness.The health care provider will perform a physical exam and ask about your symptoms. Tests that may be ordered to diagnose hyperaldosteronism include: Abdominal CT scan ECG Blood aldosterone level Blood renin activity Blood potassium level Urinary aldosterone Kidney ultrasound A procedure to insert a catheter into the veins of the adrenal glands may need to be done. This helps check which of the two adrenal glands is making too much aldosterone.Primary hyperaldosteronism caused by an adrenal gland tumor is usually treated with surgery. It can sometimes be treated with medicines. Removing the adrenal tumor may control the symptoms. Even after surgery, some people still have high blood pressure and need to take medicine. But often, the number of medicines or doses can be lowered. Limiting salt intake and taking medicine may control the symptoms without surgery. Medicines to treat hyperaldosteronism include: Drugs that block the action of aldosterone Diuretics (water pills), which help manage fluid buildup in the body Secondary hyperaldosteronism is treated with medicines (as described above) and limiting salt intake. Surgery is usually not used.The outlook for primary hyperaldosteronism is good with early diagnosis and treatment. The outlook for secondary hyperaldosteronism depends on the cause of the condition.Primary hyperaldosteronism can cause very high blood pressure, which can damage many organs, including the eyes, kidneys, heart and brain. Erection problems and gynecomastia (enlarged breasts in men) may occur with long-term use of medicines to block the effect of hyperaldosteronism. .Call for an appointment with your provider if you develop symptoms of hyperaldosteronism.Conn syndrome; Mineralocorticoid excess.Endocrine glands Endocrine glands Adrenal gland hormone secretion Adrenal gland hormone secretion.Carey RM, Padia SH. Primary mineralocorticoid excess disorders and hypertension.