Also called American Trypanosomiasis. Tropical parasitic disease caused by Trypanosoma Cruzi.Encyclopedia Entry for Chagas Disease :Chagas disease - Trypanosomiasis - American: Trypanosoma cruzi (Triatomine bugs: kissing bug or assassin bugs)Encyclopedia Entry for Chagas Disease :Chagas disease. Chagas disease is caused by the parasite Trypanosoma cruzi. It is spread by the bite of reduviid bugs, or kissing bugs, and is one of the major health problems in South America. Due to immigration, the disease also affects people in the United States. Risk factors for Chagas disease include: Living in a hut where reduviid bugs live in the walls Living in Central or South America Poverty Receiving a blood transfusion from a person who carries the parasite, but does not have active Chagas disease.Chagas disease has two phases: acute and chronic. The acute phase may have no symptoms or very mild symptoms, including: Fever General ill feeling Swelling of an eye if the bite is near the eye Swollen red area at site of the insect bite After the acute phase, the disease goes into remission. No other symptoms may appear for many years. When symptoms finally develop, they may include: Constipation Digestive problems Heart failure Pain in the abdomen Pounding or racing heart Swallowing difficulties.Physical examination can confirm the symptoms. Signs of Chagas disease may include: Disease of the heart muscle Enlarged liver and spleen Enlarged lymph nodes Irregular heartbeat Rapid heartbeat Tests include: Blood culture to look for signs of infection Chest x-ray Echocardiogram (uses sound waves to create pictures of the heart) Electrocardiogram ( ECG , tests electrical activity in the heart) Enzyme-linked immunoassay ( ELISA ) to look for signs of infection Peripheral blood smear to look for signs of infection.The acute phase and reactivated Chagas disease should be treated. Infants born with the infection should also be treated. Treating the chronic phase is recommended for children and most adults. Adults with chronic phase Chagas disease should talk to their health care provider to decide whether treatment is needed. Two drugs are used to treat this infection: benznidazole and nifurtimox. Both drugs often have side effects. The side effects may be worse in older people. They may include: Headaches and dizziness Loss of appetite and weight loss Nerve damage Problems sleeping Skin rashes.About one third of infected people who are not treated will develop chronic or symptomatic Chagas disease. It may take more than 20 years from the time of the original infection to develop heart or digestive problems. Abnormal heart rhythms may cause sudden death. Once heart failure develops, death usually occurs within several years.Chagas disease can cause these complications: Enlarged colon Enlarged esophagus with swallowing difficulty Heart disease Heart failure Malnutrition.Call for an appointment with your provider if you think you may have Chagas disease.Insect control with insecticides and houses that are less likely to have high insect populations will help control the spread of the disease. Blood banks in Central and South America screen donors for exposure to the parasite. The blood is discarded if the donor has the parasite. Most blood banks in the United States began screening for Chagas disease in 2007.Parasite infection - American trypanosomiasis.Kissing bug Kissing bug Antibodies Antibodies.Bogitsh BJ, Carter CE. Blood and tissue protozoa I: hemoflagellates.Encyclopedia Entry for Chagas Disease :Chagas Disease (American trypanosomiasis). Source of disease: Trypanosoma cruzi