Notes

Jaundice

See Liver Support, Gallbladder, Leptospirosis, Parasites General, and Flukes programs. Also see Icterus Haemolytic.SkinEncyclopedia Entry for Jaundice :Jaundice and breastfeeding. Bilirubin is a yellow pigment that is produced as the body recycles old red blood cells. The liver helps break down bilirubin so that it can be removed from the body in the stool. It can be normal for newborn babies to be a little yellow between days 1 and 5 of life. The color most often peaks around day 3 or 4. Breast milk jaundice is seen after the first week of life. It is likely caused by: Factors in a mother's milk that help a baby absorb bilirubin from the intestine Factors that keep certain proteins in the baby's liver from breaking down bilirubin Sometimes, jaundice occurs when your baby does not get enough breast milk, instead of from the breast milk itself. This kind of jaundice is different because it starts in the first few days of life. It is called 'breastfeeding failure jaundice,' 'breast-non-feeding jaundice,' or even 'starvation jaundice.' Babies who are born early (before 37 or 38 weeks) are not always able to feed well. Breastfeeding failure or breast-non-feeding jaundice may also occur when feedings are scheduled by the clock (such as, every 3 hours for 10 minutes) or when babies who show signs of hunger are given pacifiers. Breast milk jaundice may run in families. It occurs just as often in males and females and affects about a third of all newborns who get only their mother's milk.Your child's skin, and possibly the whites of the eyes (sclerae), will look yellow.Laboratory tests that may be done include: Bilirubin level (total and direct) Blood smear to look at blood cell shapes and sizes Blood type Complete blood count Reticulocyte count (number of slightly immature red blood cells) In some cases, a blood test to check for glucose-6-phosphate dehydrogenase (G6PD) may be done. G6PD is a protein that helps red blood cells work properly. These tests are done to be sure that there are no other, more dangerous causes of the jaundice. Another test that may be considered consists of stopping breastfeeding and giving formula for 12 to 24 hours. This is done to see if the bilirubin level goes down. This test is not always necessary.Treatment will depend on: Your baby's bilirubin level, which naturally rises during the first week of life How fast the bilirubin level has been going up Whether your baby was born early How your baby has been feeding How old your baby is now Often, the bilirubin level is normal for the baby's age. Newborns normally have higher levels than older children and adults. In this case, no treatment is needed, other than close follow-up. You can prevent the kind of jaundice that is caused by too little breastfeeding by making sure your baby is getting enough milk. Feed about 10 to 12 times each day, starting on the first day. Feed whenever baby is alert, sucking on the hands, and smacking the lips. This is how babies let you know they are hungry. If you wait until your baby cries, feeding will not go as well. Give babies unlimited time at each breast, as long as they are sucking and swallowing steadily. Full babies will relax, unclench their hands, and drift off to sleep. If breastfeeding is not going well, get help from a lactation consultant or your doctor as soon as possible. Babies born before 37 or 38 weeks most often need extra help. Their moms often need to express or pump to make enough milk while they are learning to breastfeed. Nursing or pumping more often (up to 12 times a day) will increase the amount of milk the baby gets. They can cause the bilirubin level to drop. Ask your doctor before deciding to give your newborn formula. It is best to keep breastfeeding. Babies need their mothers' milk. Although a baby full of formula can be less demanding, formula feeding may cause you to make less milk. If the milk supply is low because baby's demand has been low (for example, if baby was born early), you may have to use formula for a brief time. You should also use a pump to help make more breast milk until baby is better able to nurse. Spending 'skin to skin' time can also help babies feed better and help moms make more milk. In some cases, if babies aren't able to feed well, fluids are given through a vein to help increase their fluid levels and lower bilirubin levels. To help break down the bilirubin if it is too high, your baby may be placed under special blue lights (phototherapy). You may be able to do phototherapy at home.The baby should recover fully with the right monitoring and treatment. The jaundice should go away by 12 weeks of life.In true breast milk jaundice, there are no complications in most cases. However, babies with very high bilirubin levels who do not get the right medical care can have severe effects.Call your health care provider right away if you are breastfeeding and your baby's skin or eyes become yellow (jaundiced).Breast milk jaundice cannot be prevented, and it is not harmful. But when a baby's color is yellow, you must have the baby's bilirubin level checked right away. If the bilirubin level is high, it is important to make sure there are no other medical problems.Hyperbilirubinemia - breast milk; Breast milk jaundice; Breastfeeding failure jaundice.Newborn jaundice - discharge.Bili lights Bili lights Jaundiced infant Jaundiced infant Infant jaundice Infant jaundice.Holmes AV, McLeod AY, Bunik M. ABM Clinical Protocol #5: peripartum breastfeeding management for the healthy mother and infant at term, revision 2013. Breastfeed Med. 2013;8(6):469-473. PMID: 24320091 www.ncbi.nlm.nih.gov/pubmed/24320091. Lawrence RA, Lawrence RM. Breastfeeding infants with problems.Encyclopedia Entry for Jaundice :Jaundice causes. Jaundice is often a sign of a problem with the liver, gallbladder, or pancreas. Jaundice can occur when too much bilirubin builds up in the body. This may happen when: There are too many red blood cells dying or breaking down and going to the liver. The liver is overloaded or damaged. The bilirubin from the liver is not able to properly move into the digestive tract. Conditions that can cause jaundice include: Infections of the liver from a virus ( hepatitis A , hepatitis B , hepatitis C , hepatitis D , and hepatitis E) or a parasite Use of certain drugs (such as an overdose of acetaminophen) or exposure to poisons Birth defects or disorders present since birth that makes it hard for the body to breakdown bilirubin (such as Gilbert syndrome , Dubin-Johnson syndrome , Rotor syndrome, or Crigler-Najjar syndrome ) Chronic liver disease Gallstones or gallbladder disorders causing blockage of the bile duct Blood disorders Cancer of the pancreas Bile buildup in the gallbladder because of pressure in the belly area during pregnancy (jaundice of pregnancy).Causes of jaundice; Cholestasis.Lidofsky SD. Jaundice.Encyclopedia Entry for Jaundice :Jaundice. A small number of red blood cells in your body die each day, and are replaced by new ones. The liver removes the old blood cells. This creates bilirubin. The liver helps break down bilirubin so that it can be removed by the body through the stool. Jaundice can occur when too much bilirubin builds up in the body. Jaundice can occur if: Too many red blood cells are dying or breaking down and going to the liver. The liver is overloaded or damaged. The bilirubin from the liver is unable to properly move into the digestive tract. Jaundice is often a sign of a problem with the liver, gallbladder, or pancreas. Things that can cause jaundice include: Infections, most commonly viral Use of certain drugs Cancer of the liver, bile ducts or pancreas Blood disorders, gallstones, birth defects and a number of other medical conditions can lead to jaundice. For more information on the causes of jaundice see: jaundice causes.Jaundice may appear suddenly or develop slowly over time. Symptoms of jaundice commonly include: Yellow skin and the white part of the eyes (sclera) -- when jaundice is more severe, these areas may look brown Yellow color inside the mouth Dark or brown-colored urine Pale or clay-colored stools Note: If your skin is yellow and the whites of your eyes are not yellow, you may not have jaundice. Your skin can turn a yellow-to-orange color if you eat a lot of beta carotene, the orange pigment in carrots. Other symptoms depend on the disorder causing the jaundice: Cancers may produce no symptoms, or there may be fatigue, weight loss, or other symptoms. Hepatitis may produce nausea, vomiting, fatigue, or other symptoms.The health care provider will perform a physical exam. This may show liver swelling. A bilirubin blood test will be done. Other tests may include: Hepatitis virus panel to look for infection of the liver Liver function tests to determine how well the liver is working Complete blood count to check for low blood count or anemia Abdominal ultrasound Abdominal CT scan Endoscopic retrograde cholangiopancreatography (ERCP) Percutaneous transhepatic cholangiogram ( PTCA ) Liver biopsy Cholesterol level Prothrombin time.Treatment depends on the cause of the jaundice.Contact your provider if you develop jaundice.Conditions associated with jaundice; Yellow skin and eyes; Skin - yellow; Icterus; Eyes - yellow; Yellow jaundice.Jaundice Jaundice Jaundiced infant Jaundiced infant Cirrhosis of the liver Cirrhosis of the liver Bili lights Exchange transfusion - series.Berk PD, Korenblat KM. Approach to the patient with jaundice or abnormal liver tests.